In most cases, the symptoms disappear by themselves within one to four weeks. There are no specific treatments available for HSP. a skin biopsy or kidney biopsy are performed.
Less than one per cent of people who develop HSP suffer from progressive renal failure. In severe cases, constant bleeding from tiny blood vessels and the subsequent clots can damage the glomeruli to the point of failure. Without sufficient protein circulating in the blood, water collects in tissues causing oedema. Laboratory analysis may show that the child with HSP has greater than normal amounts of protein in their urine, or their urine may contain traces of blood. This means that components such as blood cells and protein molecules are lost into the urine. Glomerulonephritis is inflammation of the glomeruli. Usually, components such as blood cells and protein molecules are retained in the blood. The glomeruli are tiny filtering units inside each kidney that sieve the blood for wastes and produce urine. Glomerulonephritis is a rare complication In young children, the rash tends to target the back, buttocks and upper thighs, while in older children and adults, the rash is most common on the calves and ankles. As the person recovers, the rash fades in colour to brown, then finally disappears completely. The inflammation of capillaries in the skin causes the characteristic rash.Īt first, the rash appears as red and raised patches, which then progress to form palpable purplish lumps up to one centimetre in diameter. The vasculitis caused by HSP tends to target the capillaries of the skin and the kidneys. Vasculitis means inflammation of blood vessels. Since most bouts of HSP tend to follow upper respiratory tract infections or hay fever, it is thought that the immune systems of some individuals react abnormally to particular bacteria or viruses, though the reasons for this are unknown. The symptoms of HSP are caused by immune cells latching onto blood vessel walls and triggering irritation and inflammation. Fluid retention (oedema) affecting the hands and feet.Painful joints, especially knees and ankles.Rash may not be present on initial presentation Purple spotted skin rash (caused by bleeding into the skin), usually over the buttocks and legs.There is no treatment available to speed recovery, although corticosteroids may be used to help manage the symptoms. Usually, a child recovers from HSP with no harm done, but, in extreme cases, the kidneys are damaged to the point of renal failure. The condition typically lasts around one to four weeks, and is often marked by relapses. Generally, the older the person is, the more severe the symptoms will be.
Children (particularly boys) are most commonly affected, although the condition can develop in adults too.
Symptoms include a purple spotted skin rash, abdominal pain and gastrointestinal upsets such as diarrhoea. Another name for Henoch-Schonlein purpura is anaphylactoid purpura. The cause of this malfunction is unknown, but HSP tends to develop after an upper respiratory tract infection or a bout of hay fever. Henoch-Schonlein purpura (HSP) is a short-term inflammation of certain blood vessels (vasculitis) thought to be triggered by a malfunction of the immune system.
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